Open-source ecosystem for in vitro and microphysiological systems
Save the DateDecember 1-2, 2026Charlotte, North Carolina12th Annual Regenerative Manufacturing Innovation Consortium (RegMIC) Meeting: A Roadmap for Tissue Organoids and Body-on-a-Chip Manufacturing Standards
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GitHub

PhysioVerse GitHub

Explore PhysioVerse public repositories, project documentation, examples, releases, citation information, and contribution pathways.

GitHub repositories

Public repositories for PhysioVerse resources

The PhysioVerse GitHub organization organizes open resources for MPS data, standards, validation, reproducibility, protocols, and community projects. Use the project table below to open each repository and identify the contribution pathway that fits your role.

Repository entry points

  • Active project table
  • Repository READMEs and documentation
  • Issue pages for public input
  • Releases and citation information

Active projects

PhysioVerse GitHub project table

This table mirrors the current public GitHub profile and links each project directly to its repository.

TypeProjectWhat it is buildingHow the community can contribute
Open resourceToward StandardizationReference-anchored benchmarking for evaluating biological fidelity of advanced in vitro models.Review methodology, nominate benchmark datasets, suggest reference standards, contribute model examples.
Open resourceDGE Tool Choice BenchmarkReproducible benchmarking of edgeR and DESeq2 across sensitivity, robustness, biological interpretation, and cross-study performance.Reuse workflows, review reproducibility, suggest benchmark extensions, contribute analytical feedback.
Ecosystem hubPhysioVerse-OSEPublic entry point connecting the PhysioVerse ecosystem, contribution pathways, and open resources.Start from the contribution guide, suggest improvements, connect relevant public resources.
DataMPS Data CommonsCommunity-curated discovery of public MPS datasets.Nominate datasets, add accessions or DOIs, correct records, identify missing datasets.
StandardsMPS Minimum Metadata StandardPractical community working draft for the minimum information needed to understand and reuse MPS data.Propose fields, review required and recommended metadata, share examples, identify existing standards.
StandardsMPS Model & System DescriptorsShared terminology and descriptors for organoids, tissue chips, OTEs, organ-on-chip, body-on-chip, and related systems.Propose definitions, identify ambiguous terminology, review descriptors, suggest ontology mappings.
StandardsMPS Experimental Conditions StandardReporting framework for experimental conditions that affect MPS interpretation and reproducibility.Suggest fields for flow, media, dose, timing, materials, environment, and stimulation.
StandardsMPS Assay & Endpoint DictionaryShared definitions for assays, biological endpoints, units, and measurement context.Nominate assays and endpoints, refine definitions, suggest units, provide public examples.
BenchmarkingMPS Reference AtlasCommunity nominations and evaluation of biological reference datasets for MPS benchmarking.Nominate reference datasets, review suitability and limitations, propose selection criteria.
ValidationMPS Validation FrameworkFit-for-purpose validation evidence and reporting considerations for MPS applications.Propose criteria, share validation studies, review evidence, suggest performance measures.
ReproducibilityMPS Reproducibility CommonsPublic evidence on cross-laboratory reproducibility, variability, and robustness.Share studies, nominate benchmark datasets, report variability factors, suggest reproducibility metrics.
Multimodal dataMPS Multimodal Data StandardWorking approach for linking omics, imaging, histology, video, functional, and sensor data.Share multimodal examples, propose linkage identifiers, define modality-specific metadata.
ProtocolsMPS Protocol CommonsCommunity discovery and organization of public MPS protocols and SOP references.Nominate protocols, connect protocols to datasets and publications, identify metadata and gaps.
Community actionMPS Community ChallengesShort, focused collaborative efforts around priority MPS data, standards, validation, and curation needs.Propose a challenge, join an active challenge, contribute evidence, help define deliverables.

Repository information

What visitors can find on GitHub

Repository pages provide structured entry points for public project information, documentation, issue-based feedback, releases, and citation details when available.

Repository README

Each project page can summarize the project scope, current resources, and practical next steps.

Issue trackers

Issue pages can collect dataset nominations, metadata suggestions, documentation requests, examples, and project feedback.

Releases and citation

Repository releases and citation metadata can help visitors reference stable versions of selected public resources.

Contribution guide

The contribution guide gives visitors a starting point for non-coding and technical participation.

GitHub organization

Visit the PhysioVerse-OSE organization

Open the organization page to view public repositories, follow project updates, and access repository-level resources.

Standards and manufacturing partners

MOSSDO and RegMIC

Connect with the organizations advancing consensus standards, validation, and regenerative manufacturing across the PhysioVerse ecosystem.