Open-source ecosystem for in vitro and microphysiological systems
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Save the DateDecember 1-2, 2026Charlotte, North Carolina12th Annual Regenerative Manufacturing Innovation Consortium (RegMIC) Meeting: A Roadmap for Tissue Organoids and Body-on-a-Chip Manufacturing Standards
About MOSSDOAbout RegMICAbout the RegMIC 2026 meeting
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Governance

PhysioVerse Governance

The long-term success of the PhysioVerse depends on governance systems that support transparency, distributed leadership, accountability, and sustainable growth using Findable, Accessible, Interoperable, and Reusable (FAIR) data principles. The PhysioVerse text is exploring a blended or federated governance models, drawing from best practices and principles established by groups like the Linux Foundation, Apache Foundation, GA4GH, and mature OSE, such as those in the telecommunications industry (e.g., O-RAN). Federated or blended models emerging as a preference governance format because it allows PhysioVerse to support community involvement and shared infrastructure without giving up vendor neutrality or industry partnerships. Given the types of research and products needed in the MPS systems domain, strong IP protection and licensing guidelines as well as long-term revenue and resource models will be critical.

Standards and manufacturing partners

MOSSDO and RegMIC

Connect with the organizations advancing consensus standards, validation, and regenerative manufacturing across the PhysioVerse ecosystem.

About MOSSDO

The Microphysiological and Organoid Systems Standards Development Organization (MOSSDO) is a federally funded multi-stakeholder initiative focused specifically on establishing consensus-based standards for organoids, microphysiological systems (MPS), and body-on-a-chip technologies. MOSSDO develops frameworks for reproducibility, validation, and interoperability, enabling these platforms to be more reliably adopted across research, regulatory, and translational settings. In coordination with enabling ecosystem efforts such as PhysioVerse, MOSSDO provides the standards foundation that supports data integration, comparability, and broader field-wide adoption.

About RegMIC

The Regenerative Manufacturing Innovation Consortium (RegMIC), founded in 2014, is a national initiative that brings together stakeholders from industry, academia, and government to advance the manufacturing, scale-up, and commercialization of regenerative technologies. Through cross-sector collaboration, RegMIC addresses key challenges in translation, including process development, regulatory alignment, and the establishment of best practices across cell, tissue, and advanced in vitro systems.