Open-source ecosystem for in vitro and microphysiological systems

Save the DateDecember 1-2, 2026Charlotte, North Carolina12th Annual Regenerative Manufacturing Innovation Consortium (RegMIC) Meeting: A Roadmap for Tissue Organoids and Body-on-a-Chip Manufacturing Standards

About MOSSDO About RegMIC About the RegMIC 2026 meeting

Community

The People and Organizations Behind PhysioVerse

PhysioVerse is built around participation from users, contributors, maintainers, curators, organizations, and translational partners.

Participation pathways

A coordinated community for open, reusable advanced model system resources

The community page highlights the roles needed to build and sustain the open ecosystem. Member spotlights, working groups, and additional participation opportunities will be added as the community expands.

Users

Search, interpret, access, and reuse approved data and resources.

Contributors

Submit dataset records, metadata, files, packages, and repository links.

Maintainers

Maintain tools, templates, documentation, examples, and release practices.

Curators

Review metadata, file records, access status, and release readiness.

Organizations

Support adoption, governance, training, and sustained participation.

Partners

Engage in translation, quality, manufacturing, and implementation pathways.

Join the ecosystem

Connect with PhysioVerse around contribution, use, training, or partnership

Start with the On-Ramp or contact the team to discuss the role that best fits your goals.

Start on the On-Ramp Contact

Standards and manufacturing partners

MOSSDO and RegMIC

Connect with the organizations advancing consensus standards, validation, and regenerative manufacturing across the PhysioVerse ecosystem.

The Microphysiological and Organoid Systems Standards Development Organization (MOSSDO) is a federally funded multi-stakeholder initiative focused specifically on establishing consensus-based standards for organoids, microphysiological systems (MPS), and body-on-a-chip technologies. MOSSDO develops frameworks for reproducibility, validation, and interoperability, enabling these platforms to be more reliably adopted across research, regulatory, and translational settings. In coordination with enabling ecosystem efforts such as PhysioVerse, MOSSDO provides the standards foundation that supports data integration, comparability, and broader field-wide adoption.

The Regenerative Manufacturing Innovation Consortium (RegMIC), founded in 2014, is a national initiative that brings together stakeholders from industry, academia, and government to advance the manufacturing, scale-up, and commercialization of regenerative technologies. Through cross-sector collaboration, RegMIC addresses key challenges in translation, including process development, regulatory alignment, and the establishment of best practices across cell, tissue, and advanced in vitro systems.